How a health scare led to a $275M biotech company

This Week at YC

October 2, 2023

“What I hope to do is get you to unlearn some of the fundraising advice that you’ve learned so far...”

In his 10+ years as a Partner at YC, Michael Seibel has done over two thousand YC interviews. At this point, he knows better than just about anyone on the planet what makes a startup pitch stand out.

So what's the main thing people get wrong? Is it not having a super flashy pitch deck? No. Is it not coming in with enough energy or pizazz? Nope.

It's not being able to explain, concisely, what your startup does. It's that simple.

“If I don’t know what your company does, I can’t fund you." 

At the SaaStr conference just a few weeks back, Michael gave a 45-minute talk on the dos and don'ts of pitching a seed stage startup. It's great, and absolutely packed with concrete advice and real-world examples. Find it here.

📺 The Latest

Featured content from the YC Library

Backstory: Surbhi Sarna

When Surbhi Sarna was just thirteen, a sudden and excruciating pain in her side changed her life. The pain led to weeks of testing and flimsy diagnoses that would ultimately boil down to “Cancer, maybe?”

Flash forward to today and Surbhi is a Group Partner at YC, mentoring a generation of healthcare founders. Connecting these two points in time is one of the most intense startup stories we’ve ever heard — but it’s one best told by Surbhi herself.

In this debut episode of ‘Backstory’, she’ll do just that. Learn more about this new series here.

🌎 YC Community

Highlights and news from around YC
NYT explores how Can of Soup (S23) and other social apps are embracing AI
New York Times
Slope (S21) raises $30 Million from Sam Altman and others to ramp up AI tools
Forbes
"This isn't just a fundraising announcement, it's the real story of Slope, from starting with a bad idea, to pivoting to a good one, to eventually raising $187M.

The thing that finally worked was the fifth idea of their second company."


YC Group Partner Jared Friedman on Twitter 
Roblox acquires voice moderation startup Speechly (W22) 
TechCrunch

🚀 The Launchpad

Some of the most recent YC companies and product launches 
Meet Martin, a better Siri with an LLM brain.
S2023
Dramatically better search and ads for top marketplaces and e-commerce apps
W2021
Find more YC companies and discover new products

🔥 Hacker News

Top posts from this week
  1. WiFi without internet on a Southwest flight (jamesbvaughan.com)
    1748 points by jamesbvaughan | 644 comments

  2. Raspberry Pi 5 (www.raspberrypi.com)
    1663 points by chabes | 1013 comments

  3. Richard Stallman reveals he has cancer in the GNU 40 Hacker Meeting talk [video] (audio-video.gnu.org)
    1354 points by fury999io | 768 comments

  4. FTC sues Amazon for illegally maintaining monopoly power (www.ftc.gov)
    1137 points by marcopolis | 896 comments

  5. Draggable objects (www.redblobgames.com)
    1042 points by stefankuehnel | 139 comments

  6. A journey into the shaken baby syndrome/abusive head trauma controversy (www.cambridgeblog.org)
    1012 points by rossant | 594 comments

  7. The Philips Hue ecosystem is collapsing (rachelbythebay.com)
    959 points by picture | 706 comments

  8. Mistral 7B (mistral.ai)
    873 points by jasondavies | 615 comments

  9. Everything authenticated by Microsoft is tainted (graz.social)
    761 points by ColinWright | 369 comments

  10. I got robbed of my first kernel contribution (ariel-miculas.github.io)
    702 points by kkapelon | 690 comments

  11.  
Read more on Hacker News
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40 YC founders weigh in on the state of AI

Monday, September 25, 2023

What are the best uses for AI today? Where does it still fall short? This Week at YC September 25, 2023 This past week was an incredible one at YC. With S23 coming to a close, we wrapped things up with

Dalton & Michael on why you shouldn't copy your idols

Tuesday, September 19, 2023

A new episode of D&M is here! This Week at YC September 19, 2023 📺 Why You Shouldn't Copy Your Tech Idols For this episode of Dalton & Michael, the pair dig into why some advice givers

Meet the YC Summer 2023 Batch

Tuesday, September 12, 2023

It's one of the strongest YC batches ever. This Week at YC September 12, 2023 This past week was a big one for YC's S23 class. As this batch wraps up, it was time for Demo Day — the day (or

Demo Day approaches!

Tuesday, September 5, 2023

Plus a new episode of Design Review This Week at YC September 5, 2023 It's nearly time for Demo Day! Over 200 companies joined YC for the S23 batch, and this week many of them will present what

How do investors really feel about YC?

Monday, August 28, 2023

Dalton & Michael dig in. This Week at YC August 28, 2023 🧡 Dalton & Michael on why investors (secretly) love Y Combinator YC is undeniably an integral part of the venture capital ecosystem,

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