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Hi friends 👋,

Happy Friday and welcome to our 16th Weekly Dose of Optimism. We kicked off the weekend last night by hosting a NYC Tech Week happy hour, in partnership with Not Boring Capital portfolio company Bridgesplit. After meeting so many founders and folks in the NYC tech space, it’s hard to not have a bit of optimism in our step this morning.

Let’s get to it.

(1) podcast.ai

Joe Rogan interviews Steve Jobs play.ht Episode

Another day, another mind-blowing AI project hitting the internet. This time it was a 20 minute deepfake podcast conversation between Joe Rogan and Steve Jobs. The podcast was created by the team from Play.ht, a text-to-voice generator, which used thousands of hours of the Joe Rogan Experience audio and publicly available internet videos of Jobs to create a relatively realistic (and very listenable) conversation between the two. As someone who has listened to more JRE than I’d like to admit, this blew me away: the tone of voice, speech cadence, and even style of joke were pretty much spot on. The AI models behind the podcast are based on similar concepts to DALL-E and GPT models, and allow the language generator to imitate human’s tones and emotions.

The team plans on dropping a new deepfake podcast every week with new guests — both dead and alive. This is as Black Mirror-ish as any of the AI content generators to-date and about as close to bringing back someone from the dead as we’ve ever seen.

Please keep us professional content creators in your thoughts and prayers during these trying times.

(2) Human ‘mini-brains’ implanted in rats prompt excitement — and concern

Sara Reardon for Nature

Miniature human brain-like structures transplanted into rats can send signals and respond to environmental cues picked up by the rats’ whiskers, according to a study¹. This demonstration that neurons grown from human stem cells can interface with nerve cells in live rodents could lead to a way to test therapies for human brain disorders.

This is one of those scientific breakthroughs that seem really interesting, but so far away impacting our actual lives that it’s hard to care about. Cool, we transplanted human brain cells into a rat’s brain, where the human cells continued to grow and integrate with the rat’s brain. Rat stuff happens all the time in labs. Very impressive, but not exactly changing my life in the next couple of years.

But this could be one of the more groundbreaking (or at least thought provoking) developments in brain science ever — the researchers basically just a) created a new humanoid and b) depending on your ethical standards, created a new species on which highly relevant brain experiments can be carried out.

How much of a rat’s brain can consist of human cells before it becomes a human brain? Would we be willing to perform experimental research on a living human brain, if that human brain was previously enclosed within a rat’s skull?

We’re likely far off from needing to confront these exact questions — “Last year, a panel organized by the US National Academies of Sciences, Engineering, and Medicine released a report concluding that human brain organoids are still too primitive to become conscious, attain human-like intelligence or acquire other abilities that might require legal regulation” — but this discovery will, in the short-term, likely advance more incremental but important research on how the human brain functions.

(3) London, U.S. scientists suggest cognition far more than neuron processing in the brain

Marjorie Hecht for Current Science Daily

The authors challenge the idea that "only the neuronal cells in the brain have the exclusive ability to `learn' or `cognize.'" Instead, they focus on cellular processing and look at cognition as a "multiscale web of dynamic information processing distributed across a vast array of complex cellular (e.g. neuronal, immune and others) and network systems operating across the entire body, and not just in the brain.

While you’re off philosophizing about rat-bodied humanoids, a group of scientists are calling into question the very nature of “thinking.” Traditionally, cognition is thought to be the domain of the brain. But research (or at least interpretations of research) suggests that the brain’s processes for thinking are actually much more flexible and interconnected with other systems in the body, like the immune system. Essentially, the mind and the body may be more interconnected — even at the cellular level — than previously suspected.

(4) US Chip Sanctions ‘Kneecap’ China’s Tech Industry

Will Knight for Wired

The sweeping new controls are designed to keep the country’s AI industry stuck in the dark ages while the US and other Western countries advance. The restrictions also block the export of chipmaking equipment and design software, and ban the world’s leading silicon fabs, including Taiwan’s TSMC and South Korea’s Samsung, from manufacturing advanced chips for Chinese companies.

We’ve written much about the New Cold War at Not Boring and the battlefields on which the war will be fought. The U.S. is starting to take clear and deliberate actions on a one very important front: semiconductors. If the New Cold War will be fought using AI, drones, and other advanced technologies, then semiconductors will power that war.

The first move was to start the reshoring of semiconductor fabrication, with the government pouring billions of dollars of investment and incentivizes to get both U.S. and foreign companies alike to manufacture chips in the U.S.

The second move is to restrict the flow of chips (and the technologies needed to make them) into China.

The U.S. has long led the way in the research and IP in semiconductor innovation, but China has become an increasingly large producer in recent years and, of course, has a level of geographic influence over the world’s top three producers (Japan, South Korea, and Taiwan). Biden’s playbook seems to be:

1. Reduce reliance on other countries’ fabrication capabilities by onshoring fabs in the US

2. Prevent the flow of semiconductor IP from U.S. to China

3. Prevent flow of finished good chips from U.S. allies to China.

This strategy, at least in theory, should make the U.S. a less fragile chip player and China a much weaker chip player.

Not Boring is not a policy blog — but we do think that in a New Cold War between the U.S. and China, that the U.S., and its allies, prevailing is a good thing. Democracy is better than Communism. We’ll go on record saying as much. This policy change is strong move from the Biden Administration: the U.S. is not only reducing its reliance on China, but also restricting access to one of the New Cold War’s most valuable weapons.

(5) 2022 MacArthur Fellows

The MacArthur Fellowship is a $800,000, no-strings-attached award to extraordinarily talented and creative individuals as an investment in their potential. There are three criteria for selection of Fellows:

1. Exceptional creativity

2. Promise for important future advances based on a track record of significant accomplishments

3. Potential for the Fellowship to facilitate subsequent creative work.

Last week we wrote about the Nobel Prize winners. Previously, we’ve written about the Breakthrough Prize. At Not Boring, we celebrate the institutions that celebrate the best among us. The MacArthur Foundation is one such institution. Unlike the two other prizes mentioned above, the MacArthur Fellows program — also known as the Genius Grant — doesn’t reward recipients for any specific breakthrough or past achievement. Rather, the program recognizes the potential — the genius — that lives inside a select group of creative professionals, and grants them the financial freedom to unleash that genius full throttle. It’s almost like VC, but for creative individuals rather than companies.

This year’s 25 recipients include an artist, an astrodynamicist, a synthetic inorganic chemist, and a sociologist/criminologist/social worker, pointing to the myriad forms and expressions of genius. Among them is June Huh, the high school drop out poetic mathematician who we covered when he won the Fields Medal earlier this year. Big year for June.

The program has had a few big bets pay off in the past including, famously, Lin-Manuel Miranda. Had that been an investment rather than a grant, it would have been a lucrative one: the genius grant allowed Miranda the time and resources to work on Hamilton, which has become a billion dollar franchise.

That’s all for this week. If you enjoyed this week’s email, please share it with a friend or two!

We’ll be back in your inbox 9am EST on Monday morning. Enjoy the weekend.

Packy